Special Situation

Quitting While Pregnant

Smoking in pregnancy raises risks for mother and baby, and quitting at any point helps. Behavioral support is the first-line approach; medications are used only under professional supervision.

Why this group is different

Pregnancy changes the stakes and the options: the harms of continued smoking affect the developing baby (low birth weight, preterm birth, complications), while medication choices require extra caution because of fetal exposure considerations. The sooner quitting happens, the greater the benefit.

Recommended approach

  • Start with behavioral support — face-to-face or telephone counseling is the evidence-based first line
  • Quit as early in pregnancy as possible; quitting at any stage still helps
  • For pregnant smokers who cannot quit with support alone, some guidelines allow NRT under medical supervision
  • Varenicline and bupropion are generally not recommended in pregnancy
  • Coordinate all medication decisions with prenatal care providers

What the evidence says

USPSTF and NICE guidance prioritize behavioral support for pregnant smokers. Cochrane reviews find psychosocial interventions effective in pregnancy. Evidence on NRT in pregnancy is less extensive than in non-pregnant adults; where recommended, it is used under supervision and weighed against the known harms of continued smoking.

Evidence strength: Moderate

Medication notes

NRT is considered in some national guidelines when behavioral support alone fails, under medical supervision. Varenicline and bupropion are generally avoided in pregnancy. E-cigarettes are not a recommended cessation aid in pregnancy. Any medication during pregnancy should be decided with a healthcare professional.

Community experience

Community reports describe pregnancy as a uniquely powerful motivator, with many successful quits motivated by the baby's health. Some report quitting cold turkey successfully; others describe strong cravings alongside pregnancy-related stress.

Key cautions

  • Do not start or change any medication in pregnancy without medical advice
  • Stopping smoking abruptly is safe in pregnancy — nicotine withdrawal is not medically dangerous
  • Support from partners and household members matters; a smoke-free home helps prevent return to smoking

Sources: Chamberlain et al., Cochrane Review (2017) — psychosocial interventions for pregnant smokers; USPSTF (2021) recommendation statement; NICE NG209 (2021); WHO (2024) clinical treatment guideline · Last reviewed: October 2026

Every situation is individual

This page explains the evidence — your clinician can apply it to your case.